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Drug-induced cell cycle modulation leading to cell-cycle arrest, nuclear mis-segregation, or endoreplication

BACKGROUND: Cancer cell responses to chemotherapeutic agents vary, and this may reflect different defects in DNA repair, cell-cycle checkpoints, and apoptosis control. Cytometry analysis only quantifies dye-incorporation to examine DNA content and does not reflect the biological complexity of the ce...

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Detalles Bibliográficos
Autores principales:	Sakaue-Sawano, Asako, Kobayashi, Tamiyo, Ohtawa, Kenji, Miyawaki, Atsushi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277280/ https://www.ncbi.nlm.nih.gov/pubmed/21226962 http://dx.doi.org/10.1186/1471-2121-12-2

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