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Vasoactive Intestinal Peptide Knockout (VIP KO) mouse model of sulfite-sensitive asthma: up-regulation of novel lung carbonyl reductase

BACKGROUND: We earlier reported spontaneous features of asthma in Vasoactive Intestinal Peptide knockout mice (VIP KO): 1) peribronchiolar airway inflammation, with accumulation of lymphocytes and eosinophils, 2) pro-inflammatory cytokine production of IL-5, IL-6, with IFN-γ, and 3) airway hyper-res...

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Detalles Bibliográficos
Autores principales:	Szema, Anthony M, Hamidi, Sayyed A, Koller, Antonius, Martin, Dwight W
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277465/ https://www.ncbi.nlm.nih.gov/pubmed/22103391 http://dx.doi.org/10.1186/1471-2172-12-66

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