Complex-disease networks of trait-associated single-nucleotide polymorphisms (SNPs) unveiled by information theory

OBJECTIVE: Thousands of complex-disease single-nucleotide polymorphisms (SNPs) have been discovered in genome-wide association studies (GWAS). However, these intragenic SNPs have not been collectively mined to unveil the genetic architecture between complex clinical traits. The authors hypothesize t...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Haiquan, Lee, Younghee, Chen, James L, Rebman, Ellen, Li, Jianrong, Lussier, Yves A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Group 2012
Materias:
Research and Applications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277620/
https://www.ncbi.nlm.nih.gov/pubmed/22278381
http://dx.doi.org/10.1136/amiajnl-2011-000482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277620/
https://www.ncbi.nlm.nih.gov/pubmed/22278381
http://dx.doi.org/10.1136/amiajnl-2011-000482

Ejemplares similares