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Complex-disease networks of trait-associated single-nucleotide polymorphisms (SNPs) unveiled by information theory

OBJECTIVE: Thousands of complex-disease single-nucleotide polymorphisms (SNPs) have been discovered in genome-wide association studies (GWAS). However, these intragenic SNPs have not been collectively mined to unveil the genetic architecture between complex clinical traits. The authors hypothesize t...

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Detalles Bibliográficos
Autores principales:	Li, Haiquan, Lee, Younghee, Chen, James L, Rebman, Ellen, Li, Jianrong, Lussier, Yves A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Group 2012
Materias:	Research and Applications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277620/ https://www.ncbi.nlm.nih.gov/pubmed/22278381 http://dx.doi.org/10.1136/amiajnl-2011-000482

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