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Multiplex meta-analysis of RNA expression to identify genes with variants associated with immune dysfunction
OBJECTIVE: We demonstrate a genome-wide method for the integration of many studies of gene expression of phenotypically similar disease processes, a method of multiplex meta-analysis. We use immune dysfunction as an example disease process. DESIGN: We use a heterogeneous collection of datasets acros...
Autores principales: | Morgan, Alexander A, Pyrgos, Vasilios J, Nadeau, Kari C, Williamson, Peter R, Butte, Atul Janardhan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277634/ https://www.ncbi.nlm.nih.gov/pubmed/22319178 http://dx.doi.org/10.1136/amiajnl-2011-000657 |
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