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A phase II study of cell cycle inhibitor UCN-01 in patients with metastatic melanoma: a California Cancer Consortium trial

Background Genetic abnormalities in cell cycle control are common in malignant melanoma. UCN-01 (7-hydroxystaurosporine) is an investigational agent that exhibits antitumor activity by perturbing the cancer cell cycle. A patient with advanced melanoma experienced a partial response in a phase I tria...

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Detalles Bibliográficos
Autores principales:	Li, Tianhong, Christensen, Scott D., Frankel, Paul H., Margolin, Kim A., Agarwala, Sanjiv S., Luu, Thehang, Mack, Philip C., Lara, Primo N., Gandara, David R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2010
Materias:	Phase II Studies
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277821/ https://www.ncbi.nlm.nih.gov/pubmed/20967484 http://dx.doi.org/10.1007/s10637-010-9562-8

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