Two Immunoglobulin Tandem Proteins with a Linking β-Strand Reveal Unexpected Differences in Cooperativity and Folding Pathways

The study of the folding of single domains, in the context of their multidomain environment, is important because more than 70% of eukaryotic proteins are composed of multiple domains. The structures of the tandem immunoglobulin (Ig) domain pairs A164–A165 and A168–A169, from the A-band of the giant...

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Detalles Bibliográficos
Autores principales: Steward, Annette, Chen, Qing, Chapman, Robert I., Borgia, Madeleine B., Rogers, Joseph M., Wojtala, Alexsandra, Wilmanns, Matthias, Clarke, Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277889/
https://www.ncbi.nlm.nih.gov/pubmed/22197372
http://dx.doi.org/10.1016/j.jmb.2011.12.012

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