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Efficacy and safety of prolonged-release melatonin for insomnia in middle-aged and elderly patients with hypertension: a combined analysis of controlled clinical trials
BACKGROUND: Add-on prolonged-release melatonin (PRM) in antihypertensive therapy has been shown to ameliorate nocturnal hypertension. Hypertension is a major comorbidity among insomnia patients. The efficacy and safety of PRM for primary insomnia in patients aged 55 years and older who are treated w...
Autores principales: | Lemoine, Patrick, Wade, Alan G, Katz, Amnon, Nir, Tali, Zisapel, Nava |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278206/ https://www.ncbi.nlm.nih.gov/pubmed/22346363 http://dx.doi.org/10.2147/IBPC.S27240 |
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