Host cell and expression engineering for development of an E. coli ketoreductase catalyst: Enhancement of formate dehydrogenase activity for regeneration of NADH

BACKGROUND: Enzymatic NADH or NADPH-dependent reduction is a widely applied approach for the synthesis of optically active organic compounds. The overall biocatalytic conversion usually involves in situ regeneration of the expensive NAD(P)H. Oxidation of formate to carbon dioxide, catalyzed by forma...

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Detalles Bibliográficos
Autores principales: Mädje, Katharina, Schmölzer, Katharina, Nidetzky, Bernd, Kratzer, Regina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278346/
https://www.ncbi.nlm.nih.gov/pubmed/22236335
http://dx.doi.org/10.1186/1475-2859-11-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278346/
https://www.ncbi.nlm.nih.gov/pubmed/22236335
http://dx.doi.org/10.1186/1475-2859-11-7

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