Multi-tyrosine kinase inhibitors in preclinical studies for pediatric CNS AT/RT: Evidence for synergy with Topoisomerase-I inhibition

BACKGROUND: Currently, Atypical Teratoid Rhabdoid Tumor (AT/RT) constitutes one of the most difficult to treat malignancies in pediatrics. Hence, new knowledge of potential targets for therapeutics and the development of novel treatment approaches are urgently needed. We have evaluated the presence...

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Detalles Bibliográficos
Autores principales: Jayanthan, Aarthi, Bernoux, Delphine, Bose, Pinaki, Riabowol, Karl, Narendran, Aru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278350/
https://www.ncbi.nlm.nih.gov/pubmed/22206574
http://dx.doi.org/10.1186/1475-2867-11-44

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278350/
https://www.ncbi.nlm.nih.gov/pubmed/22206574
http://dx.doi.org/10.1186/1475-2867-11-44

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