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EGCG Enhances the Therapeutic Potential of Gemcitabine and CP690550 by Inhibiting STAT3 Signaling Pathway in Human Pancreatic Cancer

BACKGROUND: Signal Transducer and Activator of Transcription 3 (STAT3) is an oncogene, which promotes cell survival, proliferation, motility and progression in cancer cells. Targeting STAT3 signaling may lead to the development of novel therapeutic approaches for human cancers. Here, we examined the...

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Detalles Bibliográficos
Autores principales: Tang, Su-Ni, Fu, Junsheng, Shankar, Sharmila, Srivastava, Rakesh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278426/
https://www.ncbi.nlm.nih.gov/pubmed/22348037
http://dx.doi.org/10.1371/journal.pone.0031067