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CCR5Δ32 Genotype Leads to a Th2 Type Directed Immune Response in ESRD Patients

BACKGROUND: In patients with end stage renal disease (ESRD) we observed protection from inflammation-associated mortality in CCR5Δ32 carriers, leading to CCR5 deficiency, suggesting impact of CCR5Δ32 on inflammatory processes. Animal studies have shown that CCR5 deficiency is associated with a more...

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Detalles Bibliográficos
Autores principales: Muntinghe, Friso L. H., Abdulahad, Wayel H., Huitema, Minke G., Damman, Jeffrey, Seelen, Marc A., Lems, Simon P. M., Hepkema, Bouke G., Navis, Gerjan, Westra, Johanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278436/
https://www.ncbi.nlm.nih.gov/pubmed/22348061
http://dx.doi.org/10.1371/journal.pone.0031257