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CCR5Δ32 Genotype Leads to a Th2 Type Directed Immune Response in ESRD Patients
BACKGROUND: In patients with end stage renal disease (ESRD) we observed protection from inflammation-associated mortality in CCR5Δ32 carriers, leading to CCR5 deficiency, suggesting impact of CCR5Δ32 on inflammatory processes. Animal studies have shown that CCR5 deficiency is associated with a more...
Autores principales: | Muntinghe, Friso L. H., Abdulahad, Wayel H., Huitema, Minke G., Damman, Jeffrey, Seelen, Marc A., Lems, Simon P. M., Hepkema, Bouke G., Navis, Gerjan, Westra, Johanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278436/ https://www.ncbi.nlm.nih.gov/pubmed/22348061 http://dx.doi.org/10.1371/journal.pone.0031257 |
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