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Efficacy of Different Nitric Oxide-Based Strategies in Preventing Experimental Cerebral Malaria by Plasmodium berghei ANKA

BACKGROUND: Low nitric oxide (NO) bioavailability plays a role in the pathogenesis of human as well as of experimental cerebral malaria (ECM) caused by Plasmodium berghei ANKA (PbA). ECM is partially prevented by administration of the NO-donor dipropylenetriamine NONOate (DPTA-NO) at high concentrat...

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Detalles Bibliográficos
Autores principales: Martins, Yuri C., Zanini, Graziela M., Frangos, John A., Carvalho, Leonardo J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278462/
https://www.ncbi.nlm.nih.gov/pubmed/22348145
http://dx.doi.org/10.1371/journal.pone.0032048