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Pravastatin reduces steroid-induced osteonecrosis of the femoral head in SHRSP rats

BACKGROUND AND PURPOSE: Although the definite cause of steroid-induced osteonecrosis of the femoral head (ONFH) is unknown, peripheral circulatory failure, lipid metabolism disturbance, and increased oxidative stress are considered to be possible causes. We investigated whether pravastatin as a stat...

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Detalles Bibliográficos
Autores principales: Nozaki, Yoshihiro, Kumagai, Kenji, Miyata, Noriaki, Niwa, Masami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Informa Healthcare 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278663/
https://www.ncbi.nlm.nih.gov/pubmed/22313369
http://dx.doi.org/10.3109/17453674.2011.641103