Lanosterol induces mitochondrial uncoupling and protects dopaminergic neurons from cell death in a model for Parkinson's disease

Parkinson's disease (PD) is a neurodegenerative disorder marked by the selective degeneration of dopaminergic neurons in the nigrostriatal pathway. Several lines of evidence indicate that mitochondrial dysfunction contributes to its etiology. Other studies have suggested that alterations in ste...

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Detalles Bibliográficos
Autores principales: Lim, L, Jackson-Lewis, V, Wong, L C, Shui, G H, Goh, A X H, Kesavapany, S, Jenner, A M, Fivaz, M, Przedborski, S, Wenk, M R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278725/
https://www.ncbi.nlm.nih.gov/pubmed/21818119
http://dx.doi.org/10.1038/cdd.2011.105

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