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Structure-based and ligand-based virtual screening of novel methyltransferase inhibitors of the dengue virus
BACKGROUND: The dengue virus is the most significant arthropod-borne human pathogen, and an increasing number of cases have been reported over the last few decades. Currently neither vaccines nor drugs against the dengue virus are available. NS5 methyltransferase (MTase), which is located on the sur...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278841/ https://www.ncbi.nlm.nih.gov/pubmed/22373153 http://dx.doi.org/10.1186/1471-2105-12-S13-S24 |