Stevens Johnson syndrome after carbamazepine and SJS/TEN overlap syndrome after amoxicillin: case reports and a review

We present a case of Stevens Johnson syndrome in a child after carbamazepine application and Stevens Johnson/TEN overlap syndrome in an adult after amoxicillin application. On the basis of two reported cases we review the most commonly associated drugs, the postulated pathogenesis, clinical manifest...

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Detalles Bibliográficos
Autores principales: Romańska-Gocka, Krystyna, Gocki, Jacek, Placek, Waldemar, Zegarska, Barbara, Krause, Paweł
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2010
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278957/
https://www.ncbi.nlm.nih.gov/pubmed/22371734
http://dx.doi.org/10.5114/aoms.2010.13521
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author Romańska-Gocka, Krystyna
Gocki, Jacek
Placek, Waldemar
Zegarska, Barbara
Krause, Paweł
author_facet Romańska-Gocka, Krystyna
Gocki, Jacek
Placek, Waldemar
Zegarska, Barbara
Krause, Paweł
author_sort Romańska-Gocka, Krystyna
collection PubMed
description We present a case of Stevens Johnson syndrome in a child after carbamazepine application and Stevens Johnson/TEN overlap syndrome in an adult after amoxicillin application. On the basis of two reported cases we review the most commonly associated drugs, the postulated pathogenesis, clinical manifestation and management in these severe life-threatening diseases. We especially discuss the controversial systemic corticosteroid therapy. Topical care is also discussed.
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spelling pubmed-32789572012-02-27 Stevens Johnson syndrome after carbamazepine and SJS/TEN overlap syndrome after amoxicillin: case reports and a review Romańska-Gocka, Krystyna Gocki, Jacek Placek, Waldemar Zegarska, Barbara Krause, Paweł Arch Med Sci Case Report We present a case of Stevens Johnson syndrome in a child after carbamazepine application and Stevens Johnson/TEN overlap syndrome in an adult after amoxicillin application. On the basis of two reported cases we review the most commonly associated drugs, the postulated pathogenesis, clinical manifestation and management in these severe life-threatening diseases. We especially discuss the controversial systemic corticosteroid therapy. Topical care is also discussed. Termedia Publishing House 2010-03-09 2010-03-01 /pmc/articles/PMC3278957/ /pubmed/22371734 http://dx.doi.org/10.5114/aoms.2010.13521 Text en Copyright © 2010 Termedia & Banach http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Romańska-Gocka, Krystyna
Gocki, Jacek
Placek, Waldemar
Zegarska, Barbara
Krause, Paweł
Stevens Johnson syndrome after carbamazepine and SJS/TEN overlap syndrome after amoxicillin: case reports and a review
title Stevens Johnson syndrome after carbamazepine and SJS/TEN overlap syndrome after amoxicillin: case reports and a review
title_full Stevens Johnson syndrome after carbamazepine and SJS/TEN overlap syndrome after amoxicillin: case reports and a review
title_fullStr Stevens Johnson syndrome after carbamazepine and SJS/TEN overlap syndrome after amoxicillin: case reports and a review
title_full_unstemmed Stevens Johnson syndrome after carbamazepine and SJS/TEN overlap syndrome after amoxicillin: case reports and a review
title_short Stevens Johnson syndrome after carbamazepine and SJS/TEN overlap syndrome after amoxicillin: case reports and a review
title_sort stevens johnson syndrome after carbamazepine and sjs/ten overlap syndrome after amoxicillin: case reports and a review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278957/
https://www.ncbi.nlm.nih.gov/pubmed/22371734
http://dx.doi.org/10.5114/aoms.2010.13521
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