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Modeling of Bias for the Analysis of Receptor Signaling in Biochemical Systems
[Image: see text] Ligand bias is a recently introduced concept in the receptor signaling field that underlies innovative strategies for targeted drug design. Ligands, as a consequence of conformational selectivity, produce signaling bias in which some downstream biochemical pathways are favored over...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278972/ https://www.ncbi.nlm.nih.gov/pubmed/22221218 http://dx.doi.org/10.1021/bi201308s |