Post-Synapse Model Cell for Synaptic Glutamate Receptor (GluR)-Based Biosensing: Strategy and Engineering to Maximize Ligand-Gated Ion-Flux Achieving High Signal-to-Noise Ratio

Cell-based biosensing is a “smart” way to obtain efficacy-information on the effect of applied chemical on cellular biological cascade. We have proposed an engineered post-synapse model cell-based biosensors to investigate the effects of chemicals on ionotropic glutamate receptor (GluR), which is a...

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Detalles Bibliográficos
Autores principales: Tateishi, Akito, Coleman, Sarah K., Migita, Satoshi, Keinänen, Kari, Haruyama, Tetsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279253/
https://www.ncbi.nlm.nih.gov/pubmed/22368509
http://dx.doi.org/10.3390/s120101035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279253/
https://www.ncbi.nlm.nih.gov/pubmed/22368509
http://dx.doi.org/10.3390/s120101035

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