Epstein-Barr Virus (EBV)-Associated Haemophagocytic Syndrome

We describe the case of a 17- year old female who developed fatal haemophagocytic syndrome (HPS) one month following acute infection caused by Epstein-Barr virus (EBV). Despite initiation of treatment and reduction of EBV load, laboratory signs of HPS as severe cytopenia, hypofibrinogenemia, hyperfe...

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Detalles Bibliográficos
Autores principales: Torti, Lorenza, Larocca, Luigi M., Massini, Giuseppina, Cuccaro, Annarosa, Maiolo, Elena, Santangelo, Rosaria, Bianchi, Maria, Pennisi, Mariano Alberto, Hohaus, Stefan, Teofili, Luciana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Università Cattolica del Sacro Cuore 2012
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279323/
https://www.ncbi.nlm.nih.gov/pubmed/22348190
http://dx.doi.org/10.4084/MJHID.2012.008
Descripción
Sumario:We describe the case of a 17- year old female who developed fatal haemophagocytic syndrome (HPS) one month following acute infection caused by Epstein-Barr virus (EBV). Despite initiation of treatment and reduction of EBV load, laboratory signs of HPS as severe cytopenia, hypofibrinogenemia, hyperferritinemia and hypertriglyceridemia persisted, and the patient died of multiorgan failure. HPS is a rare, but life-threatening complication of EBV infection.

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