Epstein-Barr Virus (EBV)-Associated Haemophagocytic Syndrome

We describe the case of a 17- year old female who developed fatal haemophagocytic syndrome (HPS) one month following acute infection caused by Epstein-Barr virus (EBV). Despite initiation of treatment and reduction of EBV load, laboratory signs of HPS as severe cytopenia, hypofibrinogenemia, hyperfe...

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Autores principales: Torti, Lorenza, Larocca, Luigi M., Massini, Giuseppina, Cuccaro, Annarosa, Maiolo, Elena, Santangelo, Rosaria, Bianchi, Maria, Pennisi, Mariano Alberto, Hohaus, Stefan, Teofili, Luciana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Università Cattolica del Sacro Cuore 2012
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279323/
https://www.ncbi.nlm.nih.gov/pubmed/22348190
http://dx.doi.org/10.4084/MJHID.2012.008
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author Torti, Lorenza
Larocca, Luigi M.
Massini, Giuseppina
Cuccaro, Annarosa
Maiolo, Elena
Santangelo, Rosaria
Bianchi, Maria
Pennisi, Mariano Alberto
Hohaus, Stefan
Teofili, Luciana
author_facet Torti, Lorenza
Larocca, Luigi M.
Massini, Giuseppina
Cuccaro, Annarosa
Maiolo, Elena
Santangelo, Rosaria
Bianchi, Maria
Pennisi, Mariano Alberto
Hohaus, Stefan
Teofili, Luciana
author_sort Torti, Lorenza
collection PubMed
description We describe the case of a 17- year old female who developed fatal haemophagocytic syndrome (HPS) one month following acute infection caused by Epstein-Barr virus (EBV). Despite initiation of treatment and reduction of EBV load, laboratory signs of HPS as severe cytopenia, hypofibrinogenemia, hyperferritinemia and hypertriglyceridemia persisted, and the patient died of multiorgan failure. HPS is a rare, but life-threatening complication of EBV infection.
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spelling pubmed-32793232012-02-17 Epstein-Barr Virus (EBV)-Associated Haemophagocytic Syndrome Torti, Lorenza Larocca, Luigi M. Massini, Giuseppina Cuccaro, Annarosa Maiolo, Elena Santangelo, Rosaria Bianchi, Maria Pennisi, Mariano Alberto Hohaus, Stefan Teofili, Luciana Mediterr J Hematol Infect Dis Case Reports We describe the case of a 17- year old female who developed fatal haemophagocytic syndrome (HPS) one month following acute infection caused by Epstein-Barr virus (EBV). Despite initiation of treatment and reduction of EBV load, laboratory signs of HPS as severe cytopenia, hypofibrinogenemia, hyperferritinemia and hypertriglyceridemia persisted, and the patient died of multiorgan failure. HPS is a rare, but life-threatening complication of EBV infection. Università Cattolica del Sacro Cuore 2012-01-25 /pmc/articles/PMC3279323/ /pubmed/22348190 http://dx.doi.org/10.4084/MJHID.2012.008 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Torti, Lorenza
Larocca, Luigi M.
Massini, Giuseppina
Cuccaro, Annarosa
Maiolo, Elena
Santangelo, Rosaria
Bianchi, Maria
Pennisi, Mariano Alberto
Hohaus, Stefan
Teofili, Luciana
Epstein-Barr Virus (EBV)-Associated Haemophagocytic Syndrome
title Epstein-Barr Virus (EBV)-Associated Haemophagocytic Syndrome
title_full Epstein-Barr Virus (EBV)-Associated Haemophagocytic Syndrome
title_fullStr Epstein-Barr Virus (EBV)-Associated Haemophagocytic Syndrome
title_full_unstemmed Epstein-Barr Virus (EBV)-Associated Haemophagocytic Syndrome
title_short Epstein-Barr Virus (EBV)-Associated Haemophagocytic Syndrome
title_sort epstein-barr virus (ebv)-associated haemophagocytic syndrome
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279323/
https://www.ncbi.nlm.nih.gov/pubmed/22348190
http://dx.doi.org/10.4084/MJHID.2012.008
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