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Impact of single centre status on estimates of intervention effects in trials with continuous outcomes: meta-epidemiological study
Objective To compare estimates of intervention effects between single centre and multicentre randomised controlled trials with continuous outcomes. Design Meta-epidemiological study. Data sources 26 meta-analyses totalling 292 randomised controlled trials (177 single centre, 115 multicentre) with co...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group Ltd.
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279328/ https://www.ncbi.nlm.nih.gov/pubmed/22334559 http://dx.doi.org/10.1136/bmj.e813 |