Protein disulfide isomerases contribute differentially to the endoplasmic reticulum–associated degradation of apolipoprotein B and other substrates

ER-associated degradation (ERAD) rids the early secretory pathway of misfolded or misprocessed proteins. Some members of the protein disulfide isomerase (PDI) family appear to facilitate ERAD substrate selection and retrotranslocation, but a thorough characterization of PDIs during the degradation o...

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Detalles Bibliográficos
Autores principales: Grubb, Sarah, Guo, Liang, Fisher, Edward A., Brodsky, Jeffrey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279382/
https://www.ncbi.nlm.nih.gov/pubmed/22190736
http://dx.doi.org/10.1091/mbc.E11-08-0704

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