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Protein disulfide isomerases contribute differentially to the endoplasmic reticulum–associated degradation of apolipoprotein B and other substrates
ER-associated degradation (ERAD) rids the early secretory pathway of misfolded or misprocessed proteins. Some members of the protein disulfide isomerase (PDI) family appear to facilitate ERAD substrate selection and retrotranslocation, but a thorough characterization of PDIs during the degradation o...
Autores principales: | Grubb, Sarah, Guo, Liang, Fisher, Edward A., Brodsky, Jeffrey L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279382/ https://www.ncbi.nlm.nih.gov/pubmed/22190736 http://dx.doi.org/10.1091/mbc.E11-08-0704 |
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