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Myeloid Takl Acts as a Negative Regulator of the LPS Response and Mediates Resistance to Endotoxemia
TGFβ-activated kinase 1 (TAK1), a member of the mitogen-activated protein kinase kinase kinase (MAP3K) family, is considered a key intermediate in a multitude of innate immune signaling pathways. Yet, the specific role of TAK1 in the myeloid compartment during inflammatory challenges has not been re...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279403/ https://www.ncbi.nlm.nih.gov/pubmed/22348103 http://dx.doi.org/10.1371/journal.pone.0031550 |