Global Levels of Histone Modifications in Peripheral Blood Mononuclear Cells of Subjects with Exposure to Nickel

Background: Occupational exposure to nickel (Ni) is associated with an increased risk for lung and nasal cancers. Ni compounds exhibit weak mutagenic activity, cause gene amplification, and disrupt cellular epigenetic homeostasis. However, the Ni-induced changes in global histone modification levels...

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Detalles Bibliográficos
Autores principales: Arita, Adriana, Niu, Jingping, Qu, Qingshan, Zhao, Najuan, Ruan, Ye, Nadas, Arthur, Chervona, Yana, Wu, Fen, Sun, Hong, Hayes, Richard B., Costa, Max
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279455/
https://www.ncbi.nlm.nih.gov/pubmed/22024396
http://dx.doi.org/10.1289/ehp.1104140

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