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Blockade of Endothelial-Mesenchymal Transition by a Smad3 Inhibitor Delays the Early Development of Streptozotocin-Induced Diabetic Nephropathy

OBJECTIVE: A multicenter, controlled trial showed that early blockade of the renin-angiotensin system in patients with type 1 diabetes and normoalbuminuria did not retard the progression of nephropathy, suggesting that other mechanism(s) are involved in the pathogenesis of early diabetic nephropathy...

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Detalles Bibliográficos
Autores principales:	Li, Jinhua, Qu, Xinli, Yao, Jun, Caruana, Georgina, Ricardo, Sharon D., Yamamoto, Yasuhiko, Yamamoto, Hiroshi, Bertram, John F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2010
Materias:	Pathophysiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279546/ https://www.ncbi.nlm.nih.gov/pubmed/20682692 http://dx.doi.org/10.2337/db09-1631

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