Cargando…

The Medial Amygdalar Nucleus: A Novel Glucose-Sensing Region That Modulates the Counterregulatory Response to Hypoglycemia

OBJECTIVE: To determine whether the medial amygdalar nucleus (MAN) represents a novel brain glucose-sensing region involved in the detection of hypoglycemia and generation of a counterregulatory hormone response. RESEARCH DESIGN AND METHODS: Fura-2 calcium imaging was used to assess glucose responsi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Ligang, Podolsky, Nina, Sang, Zhen, Ding, Yuyan, Fan, Xiaoning, Tong, Qingchun, Levin, Barry E., McCrimmon, Rory J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2010
Materias:	Complications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279559/ https://www.ncbi.nlm.nih.gov/pubmed/20627933 http://dx.doi.org/10.2337/db09-0995

Ejemplares similares

Amplified Hormonal Counterregulatory Responses to Hypoglycemia in Rats After Systemic Delivery of a SUR-1–Selective K(+) Channel Opener?
por: Fan, Xiaoning, et al.
Publicado: (2008)

Perifornical Hypothalamic Orexin and Serotonin Modulate the Counterregulatory Response to Hypoglycemic and Glucoprivic Stimuli
por: Otlivanchik, Oleg, et al.
Publicado: (2015)

Somatostatin Receptor Type 2 Antagonism Improves Glucagon and Corticosterone Counterregulatory Responses to Hypoglycemia in Streptozotocin-Induced Diabetic Rats
por: Yue, Jessica T.Y., et al.
Publicado: (2012)

Glucose Sensing During Hypoglycemia: Lessons From the Lab
por: McCrimmon, Rory
Publicado: (2009)

Effects of Antecedent GABA A Receptor Activation on Counterregulatory Responses to Exercise in Healthy Man
por: Hedrington, Maka S., et al.
Publicado: (2015)

Consistent Effects of Hypoglycemia on Cognitive Function in People With or Without Diabetes
por: Verhulst, Clementine E.M., et al.
Publicado: (2022)

Effects of γ-Aminobutyric Acid A Receptor Activation on Counterregulatory Responses to Subsequent Exercise in Individuals With Type 1 Diabetes
por: Hedrington, Maka S., et al.
Publicado: (2016)

Brain Insulin Action Regulates Hypothalamic Glucose Sensing and the Counterregulatory Response to Hypoglycemia
por: Diggs-Andrews, Kelly A., et al.
Publicado: (2010)

Hypoglycemia in Type 1 Diabetes
por: McCrimmon, Rory J., et al.
Publicado: (2010)

Severe Hypoglycemia–Induced Fatal Cardiac Arrhythmias Are Augmented by Diabetes and Attenuated by Recurrent Hypoglycemia
por: Reno, Candace M., et al.
Publicado: (2017)

Adrenergic Mediation of Hypoglycemia-Associated Autonomic Failure
por: Ramanathan, Ranjani, et al.
Publicado: (2011)

Hypoglycemia-activated Hypothalamic Microglia Impairs Glucose Counterregulatory Responses
por: Winkler, Zsuzsanna, et al.
Publicado: (2019)

Baroreflex Sensitivity Impairment During Hypoglycemia: Implications for Cardiovascular Control
por: Rao, Ajay D., et al.
Publicado: (2016)

Effects of Acute and Antecedent Hypoglycemia on Endothelial Function and Markers of Atherothrombotic Balance in Healthy Humans
por: Joy, Nino G., et al.
Publicado: (2015)

Hypoglycemia during moderate intensity exercise reduces counterregulatory responses to subsequent hypoglycemia
por: Cade, W. Todd, et al.
Publicado: (2016)

Brain Activation During Working Memory Is Altered in Patients With Type 1 Diabetes During Hypoglycemia
por: Bolo, Nicolas R., et al.
Publicado: (2011)

Activation of Hindbrain Neurons Is Mediated by Portal-Mesenteric Vein Glucosensors During Slow-Onset Hypoglycemia
por: Bohland, MaryAnn, et al.
Publicado: (2014)

Increased GABAergic Output in the Ventromedial Hypothalamus Contributes to Impaired Hypoglycemic Counterregulation in Diabetic Rats
por: Chan, Owen, et al.
Publicado: (2011)

Effects of Intensive Therapy and Antecedent Hypoglycemia on Counterregulatory Responses to Hypoglycemia in Type 2 Diabetes
por: Davis, Stephen N., et al.
Publicado: (2009)

Relationship Between Hypoglycemia Awareness Status on Clarke/Gold Methods and Counterregulatory Response to Hypoglycemia
por: Rubin, Nathan T, et al.
Publicado: (2022)

BAD Modulates Counterregulatory Responses to Hypoglycemia and Protective Glucoprivic Feeding
por: Osundiji, Mayowa A., et al.
Publicado: (2011)

Tmem117 in AVP neurons regulates the counterregulatory response to hypoglycemia
por: Gaspari, Sevasti, et al.
Publicado: (2023)

Dissociation Between Hormonal Counterregulatory Responses and Cerebral Glucose Metabolism During Hypoglycemia
por: Lee, John J., et al.
Publicado: (2017)

Role of Synaptic Plasticity and EphA5-EphrinA5 Interaction Within the Ventromedial Hypothalamus in Response to Recurrent Hypoglycemia
por: Szepietowska, Barbara, et al.
Publicado: (2014)

‘You have to use everything and come to some equilibrium’: a qualitative study on hypoglycemia self-management in users of continuous glucose monitor with diverse hypoglycemia experiences
por: Lin, Yu Kuei, et al.
Publicado: (2023)

The RANKL/RANK/OPG Signaling Pathway Mediates Medial Arterial Calcification in Diabetic Charcot Neuroarthropathy
por: Ndip, Agbor, et al.
Publicado: (2011)

A Parabrachial-Hypothalamic Cholecystokinin Neurocircuit Controls Counterregulatory Responses to Hypoglycemia
por: Garfield, Alastair S., et al.
Publicado: (2014)

Ghrelin does not impact the blunted counterregulatory response to recurrent hypoglycemia in mice
por: Shankar, Kripa, et al.
Publicado: (2023)

Evidence That Hyperglycemia After Recovery From Hypoglycemia Worsens Endothelial Function and Increases Oxidative Stress and Inflammation in Healthy Control Subjects and Subjects With Type 1 Diabetes
por: Ceriello, Antonio, et al.
Publicado: (2012)

Naloxone, but Not Valsartan, Preserves Responses to Hypoglycemia After Antecedent Hypoglycemia: Role of Metabolic Reprogramming in Counterregulatory Failure
por: Poplawski, Michal M., et al.
Publicado: (2011)

Modulation of β-Adrenergic Receptors in the Ventromedial Hypothalamus Influences Counterregulatory Responses to Hypoglycemia
por: Szepietowska, Barbara, et al.
Publicado: (2011)

Impaired hepatic counterregulatory response to insulin-induced hypoglycemia in hepatic denervated pigs
por: Nielsen, Michael Festersen, et al.
Publicado: (2015)

Real-time Continuous Glucose Monitoring During a Hyperinsulinemic-Hypoglycemic Clamp Significantly Underestimates the Degree of Hypoglycemia
por: Farrell, Catriona M., et al.
Publicado: (2020)

An observational study of patient characteristics and mortality following hypoglycemia in the community
por: Elwen, Francesca R, et al.
Publicado: (2015)

Glycaemic thresholds for counterregulatory hormone and symptom responses to hypoglycaemia in people with and without type 1 diabetes: a systematic review
por: Verhulst, Clementine E. M., et al.
Publicado: (2022)

Clinical characteristics and outcomes of symptomatic and asymptomatic hypoglycemia in hospitalized patients with diabetes
por: Cardona, Saumeth, et al.
Publicado: (2018)

Hypoglycemia in patient with type 2 diabetes treated with insulin: it can happen
por: Heller, Simon R, et al.
Publicado: (2020)

Residual C-peptide secretion and hypoglycemia awareness in people with type 1 diabetes
por: Wellens, Martine J, et al.
Publicado: (2021)

Amyloid-related protein changes associated with dementia differ according to severity of hypoglycemia
por: Moin, Abu Saleh Md, et al.
Publicado: (2021)

Effects of Antecedent GABA(A) Activation With Alprazolam on Counterregulatory Responses to Hypoglycemia in Healthy Humans
por: Hedrington, Maka S., et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_b4gcit1tobh1nukdvj4i4n8uo7