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G Protein–Coupled Receptor Kinase 2 Plays a Relevant Role in Insulin Resistance and Obesity

OBJECTIVE: Insulin resistance is associated with the pathogenesis of metabolic disorders as type 2 diabetes and obesity. Given the emerging role of signal transduction in these syndromes, we set out to explore the possible role that G protein–coupled receptor kinase 2 (GRK2), first identified as a G...

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Detalles Bibliográficos
Autores principales: Garcia-Guerra, Lucia, Nieto-Vazquez, Iria, Vila-Bedmar, Rocio, Jurado-Pueyo, María, Zalba, Guillermo, Díez, Javier, Murga, Cristina, Fernández-Veledo, Sonia, Mayor, Federico, Lorenzo, Margarita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279564/
https://www.ncbi.nlm.nih.gov/pubmed/20627936
http://dx.doi.org/10.2337/db10-0771