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Fetal Exposure to Maternal Type 1 Diabetes Is Associated With Renal Dysfunction at Adult Age

OBJECTIVE: In animal studies, hyperglycemia during fetal development reduces nephron numbers. We tested whether this observation translates into renal dysfunction in humans by studying renal functional reserve in adult offspring exposed in utero to maternal type 1 diabetes. RESEARCH DESIGN AND METHO...

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Detalles Bibliográficos
Autores principales: Khalil, Charbel Abi, Travert, Florence, Fetita, Sabrina, Rouzet, François, Porcher, Raphael, Riveline, Jean-Pierre, Hadjadj, Samy, Larger, Etienne, Roussel, Ronan, Vexiau, Patrick, Le Guludec, Dominique, Gautier, Jean-François, Marre, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279566/
https://www.ncbi.nlm.nih.gov/pubmed/20622173
http://dx.doi.org/10.2337/db10-0419