Navigation-guided endoscopic biopsy for pathological diagnosis for intraparenchymal pure germinoma near the ventricular trigone

BACKGROUND: The authors report a case of intraparenchymal germinoma pathologically diagnosed using navigation-guided endoscopic biopsy. CASE DESCRIPTION: A 27-year-old man had mild left hemiparesis, transcortical motor aphasia, and amnesia. Magnetic resonance (MR) imaging revealed an intraparenchyma...

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Detalles Bibliográficos
Autores principales: Onuma, Kuniyuki, Ishikawa, Eiichi, Matsuda, Masahide, Shibata, Yasushi, Satomi, Kaishi, Yamamoto, Tetsuya, Zaboronok, Alexander, Takano, Shingo, Matsumura, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279989/
https://www.ncbi.nlm.nih.gov/pubmed/22347677
http://dx.doi.org/10.4103/2152-7806.92177
Descripción
Sumario:BACKGROUND: The authors report a case of intraparenchymal germinoma pathologically diagnosed using navigation-guided endoscopic biopsy. CASE DESCRIPTION: A 27-year-old man had mild left hemiparesis, transcortical motor aphasia, and amnesia. Magnetic resonance (MR) imaging revealed an intraparenchymal mass lesion near the left ventricular trigone. Navigation-guided endoscopic biopsy was performed, and histopathology revealed large neoplastic cells immunohistochemically positive for germinoma-specific antigens, which were diagnosed as pure germinoma. Chemotherapy with whole-brain radiotherapy was performed, and the neurological symptoms did not change during the treatment. Follow-up MR imaging 1 year after the surgery showed no evidence of recurrence or dissemination. CONCLUSIONS: Navigation-guided endoscopic biopsy can be a useful technique in such intraparenchymal germinoma cases.

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