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Assessing the joint effect of population stratification and sample selection in studies of gene-gene (environment) interactions
BACKGROUND: It is well known that the presence of population stratification (PS) may cause the usual test in case-control studies to produce spurious gene-disease associations. However, the impact of the PS and sample selection (SS) is less known. In this paper, we provide a systematic study of the...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280159/ https://www.ncbi.nlm.nih.gov/pubmed/22284162 http://dx.doi.org/10.1186/1471-2156-13-5 |