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RhoA/ROCK-dependent moesin phosphorylation regulates AGE-induced endothelial cellular response

BACKGROUND: The role of advanced glycation end products (AGEs) in the development of diabetes, especially diabetic complications, has been emphasized in many reports. Accumulation of AGEs in the vasculature triggers a series of morphological and functional changes in endothelial cells (ECs) and indu...

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Detalles Bibliográficos
Autores principales: Wang, Jiping, Liu, Hongxia, Chen, Bo, Li, Qiang, Huang, Xuliang, Wang, Liqun, Guo, Xiaohua, Huang, Qiaobing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280169/
https://www.ncbi.nlm.nih.gov/pubmed/22251897
http://dx.doi.org/10.1186/1475-2840-11-7