Lower Respiratory Tract Infection Induced by a Genetically Modified Picornavirus in Its Natural Murine Host

Infections with the picornavirus, human rhinovirus (HRV), are a major cause of wheezing illnesses and asthma exacerbations. In developing a murine model of picornaviral airway infection, we noted the absence of murine rhinoviruses and that mice are not natural hosts for HRV. The picornavirus, mengov...

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Detalles Bibliográficos
Autores principales: Rosenthal, Louis A., Szakaly, Renee J., Amineva, Svetlana P., Xing, Yina, Hill, Marchel R., Palmenberg, Ann C., Gern, James E., Sorkness, Ronald L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280220/
https://www.ncbi.nlm.nih.gov/pubmed/22355409
http://dx.doi.org/10.1371/journal.pone.0032061

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