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Virtual Screening, Identification and In Vitro Testing of Novel Inhibitors of O-Acetyl-L-Serine Sulfhydrylase of Entamoeba histolytica

The explosive epidemicity of amoebiasis caused by the facultative gastrointestinal protozoan parasite Entamoeba histolytica is a major public health problem in developing countries. Multidrug resistance and side effects of various available antiamoebic drugs necessitate the design of novel antiamobe...

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Detalles Bibliográficos
Autores principales: Nagpal, Isha, Raj, Isha, Subbarao, Naidu, Gourinath, Samudrala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280239/
https://www.ncbi.nlm.nih.gov/pubmed/22355310
http://dx.doi.org/10.1371/journal.pone.0030305