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Involvement of Noradrenergic Transmission in the PVN on CREB Activation, TORC1 Levels, and Pituitary-Adrenal Axis Activity during Morphine Withdrawal

Experimental and clinical findings have shown that administration of adrenoceptor antagonists alleviated different aspects of drug withdrawal and dependence. The present study tested the hypothesis that changes in CREB activation and phosphorylated TORC1 levels in the hypothalamic paraventricular nu...

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Detalles Bibliográficos
Autores principales: Martín, Fátima, Núñez, Cristina, Marín, M. Teresa, Laorden, M. Luisa, Kovács, Krisztina J., Milanés, M. Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280277/
https://www.ncbi.nlm.nih.gov/pubmed/22355339
http://dx.doi.org/10.1371/journal.pone.0031119