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Immunomodulation of Antigen Presenting Cells Promotes Natural Regulatory T Cells That Prevent Autoimmune Diabetes in NOD Mice

Progression towards type 1 diabetes (T1D) in susceptible patients is linked to a progressive decline in the capacity of regulatory T cells (Treg) to maintain tolerance. As such, therapies aimed at redressing the failing Treg compartment have been the subject of intense investigation. Treg dysfunctio...

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Detalles Bibliográficos
Autores principales:	Richer, Martin J., Lavallée, Danielle J., Shanina, Iryna, Horwitz, Marc S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280284/ https://www.ncbi.nlm.nih.gov/pubmed/22355341 http://dx.doi.org/10.1371/journal.pone.0031153

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