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Multi-Level Targeting of the Phosphatidylinositol-3-Kinase Pathway in Non-Small Cell Lung Cancer Cells

INTRODUCTION: We assessed expression of p85 and p110α PI3K subunits in non-small cell lung cancer (NSCLC) specimens and the association with mTOR expression, and studied effects of targeting the PI3K/AKT/mTOR pathway in NSCLC cell lines. METHODS: Using Automated Quantitative Analysis we quantified e...

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Detalles Bibliográficos
Autores principales: Zito, Christopher R., Jilaveanu, Lucia B., Anagnostou, Valsamo, Rimm, David, Bepler, Gerold, Maira, Sauveur-Michel, Hackl, Wolfgang, Camp, Robert, Kluger, Harriet M., Chao, Herta H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280285/
https://www.ncbi.nlm.nih.gov/pubmed/22355357
http://dx.doi.org/10.1371/journal.pone.0031331