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Multi-Level Targeting of the Phosphatidylinositol-3-Kinase Pathway in Non-Small Cell Lung Cancer Cells
INTRODUCTION: We assessed expression of p85 and p110α PI3K subunits in non-small cell lung cancer (NSCLC) specimens and the association with mTOR expression, and studied effects of targeting the PI3K/AKT/mTOR pathway in NSCLC cell lines. METHODS: Using Automated Quantitative Analysis we quantified e...
Autores principales: | Zito, Christopher R., Jilaveanu, Lucia B., Anagnostou, Valsamo, Rimm, David, Bepler, Gerold, Maira, Sauveur-Michel, Hackl, Wolfgang, Camp, Robert, Kluger, Harriet M., Chao, Herta H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280285/ https://www.ncbi.nlm.nih.gov/pubmed/22355357 http://dx.doi.org/10.1371/journal.pone.0031331 |
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