Endothelium Derived Nitric Oxide Synthase Negatively Regulates the PDGF-Survivin Pathway during Flow-Dependent Vascular Remodeling

Chronic alterations in blood flow initiate structural changes in vessel lumen caliber to normalize shear stress. The loss of endothelial derived nitric oxide synthase (eNOS) in mice promotes abnormal flow dependent vascular remodeling, thus uncoupling mechanotransduction from adaptive vascular remod...

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Detalles Bibliográficos
Autores principales: Yu, Jun, Zhang, Yuanyuan, Zhang, Xinbo, Rudic, R. Daniel, Bauer, Philip M., Altieri, Dario C., Sessa, William C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280303/
https://www.ncbi.nlm.nih.gov/pubmed/22355372
http://dx.doi.org/10.1371/journal.pone.0031495

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280303/
https://www.ncbi.nlm.nih.gov/pubmed/22355372
http://dx.doi.org/10.1371/journal.pone.0031495

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