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Endothelium Derived Nitric Oxide Synthase Negatively Regulates the PDGF-Survivin Pathway during Flow-Dependent Vascular Remodeling
Chronic alterations in blood flow initiate structural changes in vessel lumen caliber to normalize shear stress. The loss of endothelial derived nitric oxide synthase (eNOS) in mice promotes abnormal flow dependent vascular remodeling, thus uncoupling mechanotransduction from adaptive vascular remod...
Autores principales: | Yu, Jun, Zhang, Yuanyuan, Zhang, Xinbo, Rudic, R. Daniel, Bauer, Philip M., Altieri, Dario C., Sessa, William C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280303/ https://www.ncbi.nlm.nih.gov/pubmed/22355372 http://dx.doi.org/10.1371/journal.pone.0031495 |
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