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Antimetastatic Effects of Norcantharidin on Hepatocellular Carcinoma by Transcriptional Inhibition of MMP-9 through Modulation of NF-kB Activity

BACKGROUND: The rate of morbidity and mortality of hepatocellular carcinoma (HCC) in Taiwan has not lessened because of difficulty in treating tumor metastasis. Norcantharidin (NCTD) is currently used as an anticancer drug for hepatoma, breast cancer, and colorectal adenocarcinoma. NCTD possesses va...

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Detalles Bibliográficos
Autores principales: Yeh, Chao-Bin, Hsieh, Ming-Ju, Hsieh, Yi-Hsien, Chien, Ming-Hsien, Chiou, Hui-Ling, Yang, Shun-Fa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280344/
https://www.ncbi.nlm.nih.gov/pubmed/22363545
http://dx.doi.org/10.1371/journal.pone.0031055

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