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Plk1 and CK2 Act in Concert to Regulate Rad51 during DNA Double Strand Break Repair
Homologous recombination (HR) plays an important role in the maintenance of genome integrity. HR repairs broken DNA during S and G2 phases of the cell cycle but its regulatory mechanisms remain elusive. Here, we report that Polo-like kinase 1 (Plk1), which is vital for cell proliferation and is freq...
Autores principales: | Yata, Keiko, Lloyd, Janette, Maslen, Sarah, Bleuyard, Jean-Yves, Skehel, Mark, Smerdon, Stephen J., Esashi, Fumiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280358/ https://www.ncbi.nlm.nih.gov/pubmed/22325354 http://dx.doi.org/10.1016/j.molcel.2011.12.028 |
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