Human NK Cell Up-regulation of CD69, HLA-DR, Interferon γ Secretion and Cytotoxic Activity by Plasmacytoid Dendritic Cells is Regulated through Overlapping but Different Pathways

Human plasmacytoid dendritic cells secrete high levels of IFNα and are thus implicated in the activation of NK cells. Activated NK cells are characterised by the up-regulation of CD69 and MHC class II DR expression, secretion of IFN γ and enhanced cytotoxicity. We show that pDC mediate these process...

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Detalles Bibliográficos
Autores principales: Benlahrech, Adel, Donaghy, Heather, Rozis, George, Goodier, Martin, Klavinskis, Linda, Gotch, Frances, Patterson, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280753/
https://www.ncbi.nlm.nih.gov/pubmed/22389607
http://dx.doi.org/10.3390/s90100386

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