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Gene expression induced by Toll-like receptors in macrophages requires the transcription factor NFAT5

Toll-like receptors (TLRs) engage networks of transcriptional regulators to induce genes essential for antimicrobial immunity. We report that NFAT5, previously characterized as an osmostress responsive factor, regulates the expression of multiple TLR-induced genes in macrophages independently of osm...

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Detalles Bibliográficos
Autores principales:	Buxadé, Maria, Lunazzi, Giulia, Minguillón, Jordi, Iborra, Salvador, Berga-Bolaños, Rosa, del Val, Margarita, Aramburu, José, López-Rodríguez, Cristina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280876/ https://www.ncbi.nlm.nih.gov/pubmed/22312110 http://dx.doi.org/10.1084/jem.20111569

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