Cargando…

Microbiota-induced IL-1β, but not IL-6, is critical for the development of steady-state T(H)17 cells in the intestine

T(H)17 cells are a lineage of CD4(+) T cells that are critical for host defense and autoimmunity by expressing the cytokines IL-17A, IL-17F, and IL-22. A feature of T(H)17 cells at steady state is their ubiquitous presence in the lamina propria of the small intestine. The induction of these steady-s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shaw, Michael H., Kamada, Nobuhiko, Kim, Yun-Gi, Núñez, Gabriel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2012
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280878/ https://www.ncbi.nlm.nih.gov/pubmed/22291094 http://dx.doi.org/10.1084/jem.20111703

Ejemplares similares

Commensal-dependent expression of IL-25 regulates the IL-23–IL-17 axis in the intestine
por: Zaph, Colby, et al.
Publicado: (2008)

Autoantibodies against IL-17A, IL-17F, and IL-22 in patients with chronic mucocutaneous candidiasis and autoimmune polyendocrine syndrome type I
por: Puel, Anne, et al.
Publicado: (2010)

Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides
por: Liang, Spencer C., et al.
Publicado: (2006)

Lymphoid tissue inducer–like cells are an innate source of IL-17 and IL-22
por: Takatori, Hiroaki, et al.
Publicado: (2009)

IL-17 can promote tumor growth through an IL-6–Stat3 signaling pathway
por: Wang, Lin, et al.
Publicado: (2009)

Mutations in STAT3 and IL12RB1 impair the development of human IL-17–producing T cells
por: de Beaucoudrey, Ludovic, et al.
Publicado: (2008)

IL-6–dependent spontaneous proliferation is required for the induction of colitogenic IL-17–producing CD8(+) T cells
por: Tajima, Masaki, et al.
Publicado: (2008)

A crucial role for interleukin (IL)-1 in the induction of IL-17–producing T cells that mediate autoimmune encephalomyelitis
por: Sutton, Caroline, et al.
Publicado: (2006)

IL-17 produced by Paneth cells drives TNF-induced shock
por: Takahashi, Nozomi, et al.
Publicado: (2008)

Role of IL-17 and regulatory T lymphocytes in a systemic autoimmune disease
por: Lohr, Jens, et al.
Publicado: (2006)

IL-9 as a mediator of Th17-driven inflammatory disease
por: Nowak, Elizabeth C., et al.
Publicado: (2009)

A novel subset of mouse NKT cells bearing the IL-17 receptor B responds to IL-25 and contributes to airway hyperreactivity
por: Terashima, Asuka, et al.
Publicado: (2008)

Interleukin (IL)-4 inhibits IL-10 to promote IL-12 production by dendritic cells
por: Yao, Yongxue, et al.
Publicado: (2005)

IL-7 and IL-15 independently program the differentiation of intestinal CD3(−)NKp46(+) cell subsets from Id2-dependent precursors
por: Satoh-Takayama, Naoko, et al.
Publicado: (2010)

Gut epithelial IL-27 confers intestinal immunity through the induction of intraepithelial lymphocytes
por: Lin, Chia-Hao, et al.
Publicado: (2021)

Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice
por: Chalaris, Athena, et al.
Publicado: (2010)

STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing
por: Pickert, Geethanjali, et al.
Publicado: (2009)

Divergent Pro- and Antiinflammatory Roles for IL-23 and IL-12 in Joint Autoimmune Inflammation
por: Murphy, Craig A., et al.
Publicado: (2003)

IL-31–IL-31R interactions negatively regulate type 2 inflammation in the lung
por: Perrigoue, Jacqueline G., et al.
Publicado: (2007)

Identification of an IL-17–producing NK1.1(neg) iNKT cell population involved in airway neutrophilia
por: Michel, Marie-Laure, et al.
Publicado: (2007)

IL-17–induced CXCL12 recruits B cells and induces follicle formation in BALT in the absence of differentiated FDCs
por: Fleige, Henrike, et al.
Publicado: (2014)

cDC1-derived IL-27 regulates small intestinal CD4(+) T cell homeostasis in mice
por: Ahmadi, Fatemeh, et al.
Publicado: (2022)

IFN-λ resolves inflammation via suppression of neutrophil infiltration and IL-1β production
por: Blazek, Katrina, et al.
Publicado: (2015)

Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells
por: Seddiki, Nabila, et al.
Publicado: (2006)

The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4(+) T cells
por: Dienz, Oliver, et al.
Publicado: (2009)

T cell self-reactivity forms a cytokine milieu for spontaneous development of IL-17(+) Th cells that cause autoimmune arthritis
por: Hirota, Keiji, et al.
Publicado: (2007)

IL-33 reduces the development of atherosclerosis
por: Miller, Ashley M., et al.
Publicado: (2008)

Blimp-1 directly represses Il2 and the Il2 activator Fos, attenuating T cell proliferation and survival
por: Martins, Gislâine A., et al.
Publicado: (2008)

Retinoic acid expression associates with enhanced IL-22 production by γδ T cells and innate lymphoid cells and attenuation of intestinal inflammation
por: Mielke, Lisa A., et al.
Publicado: (2013)

Repression of interleukin-4 in T helper type 1 cells by Runx/Cbfβ binding to the Il4 silencer
por: Naoe, Yoshinori, et al.
Publicado: (2007)

Interleukin (IL)-4–independent Induction of Immunoglobulin (Ig)E, and Perturbation of T Cell Development in Transgenic Mice Expressing IL-13
por: Emson, Claire L., et al.
Publicado: (1998)

Inhibition of NK cell activity by IL-17 allows vaccinia virus to induce severe skin lesions in a mouse model of eczema vaccinatum
por: Kawakami, Yuko, et al.
Publicado: (2009)

Loss of the lupus autoantigen Ro52/Trim21 induces tissue inflammation and systemic autoimmunity by disregulating the IL-23–Th17 pathway
por: Espinosa, Alexander, et al.
Publicado: (2009)

A late IL-33 response after exposure to Schistosoma haematobium antigen is associated with an up-regulation of IL-13 in human eosinophils
por: Wilson, S, et al.
Publicado: (2013)

IL-12– and IL-23–modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition
por: Kroenke, Mark A., et al.
Publicado: (2008)

Murine Macrophages Secrete Interferon γ upon Combined Stimulation with Interleukin (IL)-12 and IL-18: A Novel Pathway of Autocrine Macrophage Activation
por: Munder, Markus, et al.
Publicado: (1998)

FAS Engagement Induces the Maturation of Dendritic Cells (Dcs), the Release of Interleukin (Il)-1β, and the Production of Interferon γ in the Absence of IL-12 during Dc–T Cell Cognate Interaction: A New Role for FAS Ligand in Inflammatory Responses
por: Rescigno, Maria, et al.
Publicado: (2000)

CRTAM controls residency of gut CD4(+)CD8(+) T cells in the steady state and maintenance of gut CD4(+) Th17 during parasitic infection
por: Cortez, Victor S., et al.
Publicado: (2014)

NF90 regulates inducible IL-2 gene expression in T cells
por: Shi, Lingfang, et al.
Publicado: (2007)

Prevention of UV radiation–induced immunosuppression by IL-12 is dependent on DNA repair
por: Schwarz, Agatha, et al.
Publicado: (2005)

Cannot write session to /tmp/vufind_sessions/sess_b9d8bt7m51o62sijd0jlnktqq5