Genome-Wide Association Study Identifies Novel Loci Associated with Circulating Phospho- and Sphingolipid Concentrations

Phospho- and sphingolipids are crucial cellular and intracellular compounds. These lipids are required for active transport, a number of enzymatic processes, membrane formation, and cell signalling. Disruption of their metabolism leads to several diseases, with diverse neurological, psychiatric, and...

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Detalles Bibliográficos
Autores principales: Demirkan, Ayşe, van Duijn, Cornelia M., Ugocsai, Peter, Isaacs, Aaron, Pramstaller, Peter P., Liebisch, Gerhard, Wilson, James F., Johansson, Åsa, Rudan, Igor, Aulchenko, Yurii S., Kirichenko, Anatoly V., Janssens, A. Cecile J. W., Jansen, Ritsert C., Gnewuch, Carsten, Domingues, Francisco S., Pattaro, Cristian, Wild, Sarah H., Jonasson, Inger, Polasek, Ozren, Zorkoltseva, Irina V., Hofman, Albert, Karssen, Lennart C., Struchalin, Maksim, Floyd, James, Igl, Wilmar, Biloglav, Zrinka, Broer, Linda, Pfeufer, Arne, Pichler, Irene, Campbell, Susan, Zaboli, Ghazal, Kolcic, Ivana, Rivadeneira, Fernando, Huffman, Jennifer, Hastie, Nicholas D., Uitterlinden, Andre, Franke, Lude, Franklin, Christopher S., Vitart, Veronique, Nelson, Christopher P., Preuss, Michael, Bis, Joshua C., O'Donnell, Christopher J., Franceschini, Nora, Witteman, Jacqueline C. M., Axenovich, Tatiana, Oostra, Ben A., Meitinger, Thomas, Hicks, Andrew A., Hayward, Caroline, Wright, Alan F., Gyllensten, Ulf, Campbell, Harry, Schmitz, Gerd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280968/
https://www.ncbi.nlm.nih.gov/pubmed/22359512
http://dx.doi.org/10.1371/journal.pgen.1002490

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