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FOXO3 Regulates CD8 T Cell Memory by T Cell-Intrinsic Mechanisms

CD8 T cell responses have three phases: expansion, contraction, and memory. Dynamic alterations in proliferation and apoptotic rates control CD8 T cell numbers at each phase, which in turn dictate the magnitude of CD8 T cell memory. Identification of signaling pathways that control CD8 T cell memory...

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Detalles Bibliográficos
Autores principales: Sullivan, Jeremy A., Kim, Eui Ho, Plisch, Erin H., Peng, Stanford L., Suresh, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280979/
https://www.ncbi.nlm.nih.gov/pubmed/22359505
http://dx.doi.org/10.1371/journal.ppat.1002533