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Deciphering the Preference and Predicting the Viability of Circular Permutations in Proteins

Circular permutation (CP) refers to situations in which the termini of a protein are relocated to other positions in the structure. CP occurs naturally and has been artificially created to study protein function, stability and folding. Recently CP is increasingly applied to engineer enzyme structure...

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Detalles Bibliográficos
Autores principales: Lo, Wei-Cheng, Dai, Tian, Liu, Yen-Yi, Wang, Li-Fen, Hwang, Jenn-Kang, Lyu, Ping-Chiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281007/
https://www.ncbi.nlm.nih.gov/pubmed/22359629
http://dx.doi.org/10.1371/journal.pone.0031791