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Rheotaxis in Larval Zebrafish Is Mediated by Lateral Line Mechanosensory Hair Cells

The lateral line sensory system, found in fish and amphibians, is used in prey detection, predator avoidance and schooling behavior. This system includes cell clusters, called superficial neuromasts, located on the surface of head and trunk of developing larvae. Mechanosensory hair cells in the cent...

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Detalles Bibliográficos
Autores principales: Suli, Arminda, Watson, Glen M., Rubel, Edwin W., Raible, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281009/
https://www.ncbi.nlm.nih.gov/pubmed/22359538
http://dx.doi.org/10.1371/journal.pone.0029727
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author Suli, Arminda
Watson, Glen M.
Rubel, Edwin W.
Raible, David W.
author_facet Suli, Arminda
Watson, Glen M.
Rubel, Edwin W.
Raible, David W.
author_sort Suli, Arminda
collection PubMed
description The lateral line sensory system, found in fish and amphibians, is used in prey detection, predator avoidance and schooling behavior. This system includes cell clusters, called superficial neuromasts, located on the surface of head and trunk of developing larvae. Mechanosensory hair cells in the center of each neuromast respond to disturbances in the water and convey information to the brain via the lateral line ganglia. The convenient location of mechanosensory hair cells on the body surface has made the lateral line a valuable system in which to study hair cell damage and regeneration. One way to measure hair cell survival and recovery is to assay behaviors that depend on their function. We built a system in which orientation against constant water flow, positive rheotaxis, can be quantitatively assessed. We found that zebrafish larvae perform positive rheotaxis and that, similar to adult fish, larvae use both visual and lateral line input to perform this behavior. Disruption or damage of hair cells in the absence of vision leads to a marked decrease in rheotaxis that recovers upon hair cell repair or regeneration.
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spelling pubmed-32810092012-02-22 Rheotaxis in Larval Zebrafish Is Mediated by Lateral Line Mechanosensory Hair Cells Suli, Arminda Watson, Glen M. Rubel, Edwin W. Raible, David W. PLoS One Research Article The lateral line sensory system, found in fish and amphibians, is used in prey detection, predator avoidance and schooling behavior. This system includes cell clusters, called superficial neuromasts, located on the surface of head and trunk of developing larvae. Mechanosensory hair cells in the center of each neuromast respond to disturbances in the water and convey information to the brain via the lateral line ganglia. The convenient location of mechanosensory hair cells on the body surface has made the lateral line a valuable system in which to study hair cell damage and regeneration. One way to measure hair cell survival and recovery is to assay behaviors that depend on their function. We built a system in which orientation against constant water flow, positive rheotaxis, can be quantitatively assessed. We found that zebrafish larvae perform positive rheotaxis and that, similar to adult fish, larvae use both visual and lateral line input to perform this behavior. Disruption or damage of hair cells in the absence of vision leads to a marked decrease in rheotaxis that recovers upon hair cell repair or regeneration. Public Library of Science 2012-02-16 /pmc/articles/PMC3281009/ /pubmed/22359538 http://dx.doi.org/10.1371/journal.pone.0029727 Text en Suli et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Suli, Arminda
Watson, Glen M.
Rubel, Edwin W.
Raible, David W.
Rheotaxis in Larval Zebrafish Is Mediated by Lateral Line Mechanosensory Hair Cells
title Rheotaxis in Larval Zebrafish Is Mediated by Lateral Line Mechanosensory Hair Cells
title_full Rheotaxis in Larval Zebrafish Is Mediated by Lateral Line Mechanosensory Hair Cells
title_fullStr Rheotaxis in Larval Zebrafish Is Mediated by Lateral Line Mechanosensory Hair Cells
title_full_unstemmed Rheotaxis in Larval Zebrafish Is Mediated by Lateral Line Mechanosensory Hair Cells
title_short Rheotaxis in Larval Zebrafish Is Mediated by Lateral Line Mechanosensory Hair Cells
title_sort rheotaxis in larval zebrafish is mediated by lateral line mechanosensory hair cells
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281009/
https://www.ncbi.nlm.nih.gov/pubmed/22359538
http://dx.doi.org/10.1371/journal.pone.0029727
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